Endocrine Abstracts

Hirata syndrome is a rare cause of spontaneous hypoglycaemia, more prevalent in Japanese population, very infrequent in Caucasian patients. It has been described that it can be triggered by medication with sulfhydryl compounds or α-lipoic acid. A 73-year-old male patient was sent to the Endocrinology Division in December 2015 because he had been presenting with episodes of sweating, palpitations and feeling hungry for 6 months; these symptoms improved when he ate carbohyd...

Carcinomas are the third most frequent cause of complications in acromegalic patients. It has been suggested that diabetes potentiates the risk of cancer. To assess the frequency and type of malignant neoplasms in acromegalic patients and control group; to evaluate, in both groups, the relationship between IGF-I/GH and the development of cancer, and between glucose metabolism and cancer in two centers of Buenos Aires, Argentina. Retrospective, cross-sectional study; medical re...

Nonfunctioning pituitary adenomas (NFAs) have no symptoms of hormonal overproduction and can be asymptomatic or have severe symptoms due to mass effects. The aim of our study was to assess clinical features and therapeutic outcomes in patients with clinically NFAs. We retrospectively collected data of 175 patients from 3 hospitals of Buenos Aires. Mean age: 51 years (r:13–90), 52% women, mean follow-up: 7.37 years. At diagnosis, clinical presentation was: visual field def...

Recent progress in surgical technology has resulted in new techniques as transoral endoscopic thyroidectomy (TOETVA) that is an option for patients’ cosmetic requests. We evaluated patients with thyroid cancer who underwent thyroidectomy by TOETVA approach and their follow-up. Retrospective study, 5 patients were included, Bethesda classification in FNAC resulted: 2 patients with VI category (CAT), 2: V CAT and 1: III CAT. All patients were operated by TOETVA between 2020...

Hypoparathyroidism is an endocrine deficiency whose substitution treatment with PTH 1-84 is only available in compassionate use in Argentina. There is a subgroup of patients in which the conventional therapy with calcium, calcitriol, phosphorous chelators, magnesium and diuretics does not reach an adequate clinical and/or biochemical compensation. Although teriparatide (PTH 1-34) is not approved for patients with hypoparathyroidism, it is a plausible therapeutic resource.<...

Warthin-like variant of papillary thyroid carcinoma is a rare histologic variant of PTC; they resemble Warthin tumor of salivary gland, frequently associated with lymphocytic thyroiditis. There is scarce literature available regarding this tumor.Clinical case: In August 2019 a 51-year-old female patient sought consult because she complained of constant pain in the anterior surface of the neck. Medical background: arterial hypertension, she had no history...

Patients with autoimmune thyroid diseases (AITDs) are likely to develop celiac disease (CD) among other autoimmune disorders. The prevalence of CD in general population is about 1–1.5% and the frequency of AITDs-CD association is about 1.2–4.8%. CD can be asymptomatic in adults. Our objectives were to determine the prevalence of CD in adult patients with AITDs and the presence of other endocrine and non-endocrine autoimmune diseases in a single center in Buenos Aires...

Giant prolactinomas are tumors with a large size >4 cm and/or prolactin levels higher than 3000 ng/ml and/or highly invasive growth. Today dopamine agonists (DA), mainly cabergoline (CAB), are the first-line choice in the treatment of these tumorsTo assess the efficacy, safety and long-term follow-up of patients with giant prolactinomas treated with DA. We retrospectively reviewed the clinical records of 33 patients with giant prolactinomas. Mea...

Craniopharyngiomas are rare lesions derived from cell remnants of Rathke’s pouch, usually localized in the sellar and suprasellar areas.Objectives: To analyze clinical, endocrine and histological features in a group of patients from Buenos Aires city. To assess efficacy, number of surgeries and complications after surgery or other treatments.Material and methods: Multicentric, retrospective, transversal study. Adult patients w...